Volume 47, Number 4, July-August 2013
Direct and inverse modeling of the cardiovascular and respiratory systems
|Page(s)||1059 - 1075|
|Published online||13 June 2013|
Inverse modelling of image-based patient-specific blood vessels: zero-pressure geometry and in vivo stress incorporation
1 Department of Flow, Heat and
Combustion Mechanics, Sint-Pietersnieuwstraat 41, 9000
2 IBiTech-bioMMeda, De Pintelaan 185, 9000 Ghent, Belgium.
In vivo visualization of cardiovascular structures is possible using medical images. However, one has to realize that the resulting 3D geometries correspond to in vivo conditions. This entails an internal stress state to be present in the in vivo measured geometry of e.g. a blood vessel due to the presence of the blood pressure. In order to correct for this in vivo stress, this paper presents an inverse method to restore the original zero-pressure geometry of a structure, and to recover the in vivo stress field of the final, loaded structure. The proposed backward displacement method is able to solve the inverse problem iteratively using fixed point iterations, but can be significantly accelerated by a quasi-Newton technique in which a least-squares model is used to approximate the inverse of the Jacobian. The here proposed backward displacement method allows for a straightforward implementation of the algorithm in combination with existing structural solvers, even if the structural solver is a black box, as only an update of the coordinates of the mesh needs to be performed.
Mathematics Subject Classification: 65D18 / 74L15 / 49Q10 / 65N21 / 90C53
Key words: Backward displacement method / inverse modelling / image-based modelling / patient-specific blood vessels / in vivo stress / prestress / zero-pressure geometry
© EDP Sciences, SMAI, 2013
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